The Resource A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr

A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr

Label
A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery
Title
A handbook for DNA-encoded chemistry
Title remainder
theory and applications for exploring chemical space and drug discovery
Statement of responsibility
edited by Robert A. Goodnow, Jr
Contributor
Editor of compilation
Subject
Language
eng
Summary
This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book: Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry Helps chemists generate and screen novel chemical libraries of large size and quality Bridges interdisciplinary areas of DNA-encoded combi
Cataloging source
DLC
Dewey number
615.1/9
Index
index present
LC call number
RS420
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Label
A handbook for DNA-encoded chemistry : theory and applications for exploring chemical space and drug discovery, edited by Robert A. Goodnow, Jr
Publication
Bibliography note
Includes bibliographical references and index
http://library.link/vocab/branchCode
  • net
Carrier category
online resource
Carrier MARC source
rdacarrier
Content category
text
Content type MARC source
rdacontent
Contents
Just enough knowledge? -- A brief history of the development of combinatorial chemistry and the emerging need for DNA-encoded chemistry -- A history of DNA-encoding -- DNA-compatible chemistry -- Foundations of a DNA-encoded library (DEL) -- Practices for synthesizing DNA-encoded libraries -- Chemical gene design for DNA-encoded libraries -- Analytical challenges for DNA-encoded library systems -- Information technology: functionality and architectures for DNA-encoding -- Theoretical considerations of the application of DNA-encoded libraries to drug discovery -- Begin with the end in mind : the hit-to-lead process -- Enumeration and visualization of large combinatorial chemical libraries -- Screening large compound collections -- Reported applications of DNA-encoded library chemistry -- Dual-pharmacophore DNA-encoded chemical libraries -- Hit identification and hit follow-up -- Using DNA to program chemical synthesis, discover new reactions, and detect ligand binding -- An outlook and the changing feasibility and economics of chemical diversity exploration with DNA-encoded combinatorial approaches -- Keeping the promise? an outlook on dna chemical library technology
Control code
ocn863127741
Extent
1 online resource
Form of item
online
Isbn
9781118487686
Lccn
2013046115
Media category
computer
Media MARC source
rdamedia
http://library.link/vocab/recordID
.b30253366
Specific material designation
remote
System control number
  • (OCoLC)863127741
  • pebcs1118487680

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
Processing Feedback ...