The Resource Bone Morphogenetic Proteins : From Local to Systemic Therapeutics, Slobodan Vukicevic, Kuber T. Sampath, editors

Bone Morphogenetic Proteins : From Local to Systemic Therapeutics, Slobodan Vukicevic, Kuber T. Sampath, editors

Label
Bone Morphogenetic Proteins : From Local to Systemic Therapeutics
Title
Bone Morphogenetic Proteins
Title remainder
From Local to Systemic Therapeutics
Statement of responsibility
Slobodan Vukicevic, Kuber T. Sampath, editors
Contributor
Subject
Language
eng
Summary
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a potential to provide protection against inflammation and fibrosis in acute and chronic injury of parenchymal tissues when applied systemically to sustain the function of kidney and liver. The application of BMPs from a local to systemic utility is a rapidly growing field, gaining interest among researchers and biotech entrepreneurs. In this volume, we summarize the advances made on the local and systemic use of BMPs including chapters covering the regulation of BMP-signalling pathways, biological actions of BMPs in bone, cartilage and teeth, as well as clinical applications and potential systemic use of BMPs for tissues beyond bone. This volume is of interest to researchers from immunology, cell biology, biochemistry, and clinicians from orthopedics and dentistry, as well as to research managers from biotech and pharmaceutical companies
Member of
Cataloging source
GW5XE
Dewey number
616.71061
Illustrations
illustrations
Index
index present
LC call number
QP552.B65
LC item number
B664 2008eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
Progress in inflammation research
Label
Bone Morphogenetic Proteins : From Local to Systemic Therapeutics, Slobodan Vukicevic, Kuber T. Sampath, editors
Publication
Bibliography note
Includes bibliographical references and index
http://library.link/vocab/branchCode
  • net
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Development of a novel compression-resistant carrier for recombinant human bone morphogenetic protein-2 (rhBMP-2) and preliminary clinical results -- Use of recombinant human BMP-2 in orthopedic trauma -- The application of recombinant human bone morphogenetic protein on absorbable collagen sponge (rhBMP-2/ACS) to reconstruction of maxillofacial bone defects -- Clinical outcomes using rhBMP-2 in spinal fusion applications -- Bone morphogenetic protein signaling is fine-tuned on multiple levels -- Dissection of bone morphogenetic protein signaling using genome-engineering tools -- Alterations of BMP signaling pathway(s) in skeletal diseases -- Signaling cross-talk by bone morphogenetic proteins -- The role and mechanisms of bone morphogenetic protein 4 and 2 (BMP-4 and BMP-2) in postnatal skeletal development -- The role of bone morphogenetic protein 4 (BMP-4) in tooth development -- Bone morphogenetic protein antagonists and kidney -- Induction of cementogenesis and periodontal ligament regeneration by the bone morphogenetic proteins -- Control of bone mass by sclerostin: Inhibiting BMP- and WNT-induced bone formation -- Bone morphogenetic proteins in cartilage biology -- Systemic administration of bone morphogenetic proteins
Control code
ocn288473605
Dimensions
unknown
Extent
1 online resource (xi, 343 pages)
Form of item
online
Isbn
9783764385521
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color)
http://library.link/vocab/ext/overdrive/overdriveId
978-3-7643-8551-4
http://library.link/vocab/recordID
.b24076259
Specific material designation
remote
System control number
  • (OCoLC)288473605
  • pebcs3764385510

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
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