The Resource Cross-genomic analysis of human disease genes, Ethan Bier, (electronic resource)

Cross-genomic analysis of human disease genes, Ethan Bier, (electronic resource)

Label
Cross-genomic analysis of human disease genes
Title
Cross-genomic analysis of human disease genes
Statement of responsibility
Ethan Bier
Creator
Speaker
Subject
Language
eng
Member of
Cataloging source
UkLU-K
Characteristic
representational
Series statement
The legacy of Drosophila genetics : from 'defining the gene' to 'analyzing genome function',
Label
Cross-genomic analysis of human disease genes, Ethan Bier, (electronic resource)
Publication
Note
  • Animated audio-visual presentation with synchronized narration
  • Title from title frames
http://library.link/vocab/branchCode
  • net
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Configuration of playback channels
monaural
Content category
two-dimensional moving image
Content type code
tdi
Content type MARC source
rdaconent
Contents
Contents: Systematic cross genomic comparison revealed that 75% of human disease genes have clear homologs in Drosophila and that approx. 30% are highly conserved sequences -- The fly is an excellent model multicellular organism for examining the mechanistic function of conserved human disease genes involved in developmental or tissue-related processes -- Normal or mutant human disease genes can be mis-expressed in the fly in localized patterns or at specific times using the GAL4-UAS mis-expression system -- Flies were used to identify candidate target proteins that are regulated by Ube3a and may contribute to Angelman syndrome -- Flies were used to examine the function and interaction of two toxins, Lethal Factor (LF) and Edema Factor (EF), that are produced by Bacillus anthracis -- LF cleaves at least two of the four Drosophila MAPKKs and inhibits the function of a third -- EF inhibits PKA dependent Hedgehog signaling in the fly wing
Control code
HST1780_1_3
Dimensions
unknown
Extent
1 online resource (1 streaming video file (65 min.)
File format
one file format
Governing access note
Access restricted to subscribers
Media category
  • video
  • computer
Media MARC source
  • rdamedia
  • rdamedia
Media type code
  • v
  • c
Medium for sound
other
Other physical details
color, sound)
Publisher number
1780
http://library.link/vocab/recordID
.b37238450
Sound
sound
Sound on medium or separate
sound on medium
Specific material designation
  • remote
  • other
System control number
  • HST178013
  • (UkLU-K)000947359
System details
  • Mode of access: World Wide Web
  • System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
Video recording format
other

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
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