The Resource EGF receptor family : targets for cancer therapeutics, Tony Burgess, (electronic resource)

EGF receptor family : targets for cancer therapeutics, Tony Burgess, (electronic resource)

Label
EGF receptor family : targets for cancer therapeutics
Title
EGF receptor family
Title remainder
targets for cancer therapeutics
Statement of responsibility
Tony Burgess
Title variation
Signaling from the EGF receptor family in normal and cancer cells
Creator
Speaker
Subject
Language
eng
Member of
Cataloging source
UkLU-K
Characteristic
representational
Series statement
Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease,
Label
EGF receptor family : targets for cancer therapeutics, Tony Burgess, (electronic resource)
Publication
Note
  • Animated audio-visual presentation with synchronized narration
  • Title from title frames
http://library.link/vocab/branchCode
  • net
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Configuration of playback channels
monaural
Content category
two-dimensional moving image
Content type code
tdi
Content type MARC source
rdaconent
Contents
Contents: The association of the Epidermal Growth Factor Receptor (EGFR) with the tumorigenic state -- The four related members of the EGFR family (EGFR, erbB2, erbB3 and erbB4) -- Signaling of the activated receptors as either homo- or heteromeric oligomers -- Activation of the EGFR by excess ligand stimulation, receptor over-expression and/or mutation in many carcinomas -- Utility of antibodies and receptor kinase inhibitors which interfere with signaling from the EGFR family as agents in cancer therapy -- The three-dimensional structures for the extracellular domains of EGFR, erbB2, erbB3 and erbB4 and the discovery that EGFR, erbB3 and erbB4 undergo major conformational transitions when interacting with their ligands -- Development of antibodies (mab806) which reduce tumor formation from cells expressing either truncated D2-7 EGFR or over-expressed EGFR by binding to the receptor in a region normally masked by the dimerization of the EGFR extracellular domain -- Use of EGFR antagonists or inhibitors to increase tumor killing by cytotoxic anti-cancer drugs and/or radiation -- Improvement of tumor killing by combining EGFR antagonists and EGFR kinase inhibitors
Control code
HST1074_1_2
Dimensions
unknown
Extent
1 online resource (1 streaming video file (45 min.)
File format
one file format
Governing access note
Access restricted to subscribers
Media category
  • video
  • computer
Media MARC source
  • rdamedia
  • rdamedia
Media type code
  • v
  • c
Medium for sound
other
Other physical details
color, sound)
Publisher number
1074
http://library.link/vocab/recordID
.b37231455
Sound
sound
Sound on medium or separate
sound on medium
Specific material designation
  • remote
  • other
System control number
  • HST107412
  • (UkLU-K)AC000390284
System details
  • Mode of access: World Wide Web
  • System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
Video recording format
other

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
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