The Resource Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists, Robert A. Copeland

Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists, Robert A. Copeland

Label
Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists
Title
Evaluation of enzyme inhibitors in drug discovery
Title remainder
a guide for medicinal chemists and pharmacologists
Statement of responsibility
Robert A. Copeland
Creator
Subject
Language
eng
Summary
Most enzymology textbooks, including his own, address biochemists and other researchers, says Copeland, a researcher in enzymology and mechanistic pharmacology at a large pharmaceutical corporation. Here he provides chemists and pharmacologists with key information to answer such questions as what opportunities for inhibitor interactions with enzym
Member of
Cataloging source
N$T
Dewey number
615/.19
Illustrations
illustrations
Index
index present
LC call number
QP601.5
LC item number
.C675 2005eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Series statement
Methods of biochemical analysis
Series volume
v. 46
Label
Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists, Robert A. Copeland
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
http://library.link/vocab/branchCode
  • net
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Why enzymes as drug targets? -- Enzyme reaction mechanisms. -- Reversible modes of inhibitor interactions with enzymes. -- Assay considerations for compound library screening. -- Lead organization and structure-activity relationships for reversible inhibitors. -- Slow binding inhibitors. -- Tight binding inhibitors. -- Irreversible enzyme inactivators. -- Appendix 1. Kinetics if biochemical reactions. -- Appendix 2. Derivation of the enzyme-ligand binding isotherm equation. -- Appendix 3. Serial dilution schemes
Control code
ocm58964965
Dimensions
unknown
Extent
1 online resource (xvii, 271 pages)
File format
unknown
Form of item
online
Isbn
9780471686965
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color)
http://library.link/vocab/ext/overdrive/overdriveId
ebl231747
Quality assurance targets
unknown
http://library.link/vocab/recordID
.b21972412
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)58964965
  • pebcs0471686964

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
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