The Resource Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins, edited by Neal S. Young, Joel Moss, (electronic resource)

Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins, edited by Neal S. Young, Joel Moss, (electronic resource)

Label
Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins
Title
Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins
Statement of responsibility
edited by Neal S. Young, Joel Moss
Title variation
PNH and the GPI-linked proteins
Contributor
Subject
Language
eng
Summary
Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients. Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins. This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins. Key Features * Outlines the chemical features of PNH * Explains the mechanism of hemolysis * Includes work on the biochemistry of glycophosphoinositol anchors * Contains descriptions of the chemistry and biophysics of GPI-anchored proteins
Additional physical form
Online version of the print title
Cataloging source
OCoLC
Dewey number
616.1/51
Illustrations
illustrations
Index
index present
LC call number
RC641.7.P37
LC item number
P37 2000eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Label
Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins, edited by Neal S. Young, Joel Moss, (electronic resource)
Publication
Antecedent source
file reproduced from original
Bibliography note
Includes bibliographical references and index
http://library.link/vocab/branchCode
  • net
Color
mixed
Contents
A brief history of PNH / Wendell Rosse -- Genetics of PNH / Lucio Luzzatto and Khedoudja Nafa -- Hemolysis in PNH / Charles J. Parker -- Thrombotic complications in PNH / Elaine M. Sloand and Neal S. Young -- Bone marrow failure in PNH / Daniel E. Dunn, Johnson M. Liu, and Neal S. Young -- Animal models of PNH / Taroh Kinoshita, Monica Bessler, and Junji Takeda -- The function of GPI-anchored proteins / Ian Okazaki and Joel Moss -- GPI in lower animals / Louis Schofield -- Synthesis of the GPI Anchor / Daniel Sevlever, Rui Chen, and M. Edward Medof -- Functional and structural organization of GPI-anchored proteins in cellular membranes / Satyajit Mayor -- Structure and function of GPI-specific phospholipases / Martin G. Low
Control code
000048130338
Dimensions
unknown
Extent
1 online resource (xiii, 279 p.)
File format
unknown
Form of item
electronic
Isbn
9780080492094
Level of compression
uncompressed
Other physical details
ill. (some col.)
http://library.link/vocab/ext/overdrive/overdriveId
81189:81189
Quality assurance targets
unknown
http://library.link/vocab/recordID
.b29941490
Reformatting quality
access
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)162129026
  • sciencedirect0080492096
System details
  • Mode of access: World Wide Web
  • System requirements: Internet connectivity, World Wide Web browser, and Adobe Acrobat

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
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