The Resource Privileged scaffolds in medicinal chemistry : design, synthesis, evaluation, editor: Stefan Bräse

Privileged scaffolds in medicinal chemistry : design, synthesis, evaluation, editor: Stefan Bräse

Label
Privileged scaffolds in medicinal chemistry : design, synthesis, evaluation
Title
Privileged scaffolds in medicinal chemistry
Title remainder
design, synthesis, evaluation
Statement of responsibility
editor: Stefan Bräse
Contributor
Editor
Subject
Language
eng
Summary
One strategy to expedite the discovery of new drugs, a process that is somewhat slow and serendipitous, is the identification and use of privileged scaffolds. This book covers the history of the discovery and use of privileged scaffolds and addresses the various classes of these important molecular fragments. The first of the benzodiazepines, a class of drugs that is powerful for treating anxiety, may not have been discovered had it not been for a chance experiment on the contents of a discarded flask found during a lab clean-up. Some years later, scientists discovered that benzodiazepine derivatives were also effective in treating other diseases. This class of molecules was the first to be described as privileged in the sense that it is especially effective at altering the course of disease. Other privileged molecular structures have since been discovered, and since these compounds are so effective at interacting with numerous classes of proteins, they may be an effective starting point to look for new drugs against the supposedly 3undruggable4 proteins. Following introductory chapters presenting an overview, a historical perspective and the theoretical background and findings, main chapters describe the structure of privileged structures in turn and discuss major drug classes associated with them and their syntheses. This book provides comprehensive coverage of the subject through chapters contributed by expert authors from both academia and industry and will be an excellent reference source for medicinal chemists of a range of disciplines and experiences
Member of
Cataloging source
UKRSC
Dewey number
615.1/9
Index
index present
LC call number
RS403
Literary form
non fiction
Nature of contents
dictionaries
Series statement
RSC drug discovery
Label
Privileged scaffolds in medicinal chemistry : design, synthesis, evaluation, editor: Stefan Bräse
Publication
Copyright
Note
Includes index
Antecedent source
unknown
http://library.link/vocab/branchCode
  • net
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Control code
ocn932123727
Dimensions
unknown
Extent
1 online resource (570 p.)
File format
unknown
Form of item
online
Isbn
9781782620303
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
c
http://library.link/vocab/ext/overdrive/overdriveId
3869:3747
Quality assurance targets
not applicable
http://library.link/vocab/recordID
.b33778760
Reformatting quality
unknown
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)932123727
  • rsc1782622241

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
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