The Resource The deeper genome : why there is more to the human genome than meets the eye, John Parrington

The deeper genome : why there is more to the human genome than meets the eye, John Parrington

Label
The deeper genome : why there is more to the human genome than meets the eye
Title
The deeper genome
Title remainder
why there is more to the human genome than meets the eye
Statement of responsibility
John Parrington
Title variation
Why there is more to the human genome than meets the eye
Creator
Author
Subject
Language
eng
Summary
Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportion of DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'? Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined
Cataloging source
N$T
Dewey number
572.86
Illustrations
illustrations
Index
index present
LC call number
QH447
LC item number
.P37 2015eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Label
The deeper genome : why there is more to the human genome than meets the eye, John Parrington
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references (pages 210-236) and indexes
http://library.link/vocab/branchCode
  • net
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
How the genome lost its junk -- The inheritors -- Life as a code -- Switches and signals -- The spacious genome -- RNA out of the shadows -- It's a jungle in there! -- The genome in 3D -- The jumping genes -- The marks of Lamarck -- Code, non-code, garbage, and junk -- Genes and disease -- What makes us human? -- The genome that became conscious -- The case for complexity
Control code
ocn906575146
Dimensions
unknown
Edition
First edition
Extent
1 online resource (v, 246 pages)
File format
unknown
Form of item
online
Isbn
9780191002465
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations
Quality assurance targets
unknown
http://library.link/vocab/recordID
.b34623814
Sound
unknown sound
Specific material designation
remote
System control number
  • (OCoLC)906575146
  • ebl0191002461

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
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