The Resource The network collective : rise and fall of a scientific paradigm, Klaus Eichmann

The network collective : rise and fall of a scientific paradigm, Klaus Eichmann

Label
The network collective : rise and fall of a scientific paradigm
Title
The network collective
Title remainder
rise and fall of a scientific paradigm
Statement of responsibility
Klaus Eichmann
Creator
Subject
Language
eng
Summary
The network paradigm dominated immunological research from the early 1970s to the late 1980s. The originator, Niels Jerne, hypothesized that the vast diversity of antibodies in each individual forms a network of mutual "idiotypic" recognition, thus regulating the immune system. In context of emerging concepts of systems biology such as cybernetics and autopoesis, the "Eigenbehavior" of the immune system fascinated an entire generation of young immunologists. But fascination led to experimental errors and overinterpretation, eventually magnifying the immune system from a mere infection-fighting device to a substrate of personality and individuality. As a result, what initially appeared as an exciting new perspective of the immune system is now viewed as a scientific vagary, and is largely abandoned. The author, himself a participant in the network vagary, begins with a description of the leading theoretical concepts on fact finding in science. This is followed by a historical account of the rise and fall of the network paradigm, complemented by personal interviews with some of the prominent protagonists. By comparing the network paradigm to other, more lasting concepts in life science, the author develops a general perspective on how solid knowledge is derived from error-prone scientific methodology, namely by exposure of scientific notions to the scrutiny of reality
Cataloging source
COO
Dewey number
616.079
Illustrations
illustrations
Index
index present
LC call number
QR186.3
LC item number
.E34 2008
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
Label
The network collective : rise and fall of a scientific paradigm, Klaus Eichmann
Publication
Bibliography note
Includes bibliographical references and index
http://library.link/vocab/branchCode
  • net
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
txt
Content type MARC source
rdacontent
Contents
Autobiographical note -- Autobiographical note -- Scientific Knowledge, Delusive or Deductive -- Realism, constructivism, and the naiveté of the experimental scientist -- Beyond underdeterminism: Popper, Kuhn, et al. -- The anthropology of science: Ludwik Fleck et al. -- The science wars -- Origins, Rise, and Fall of the Network Paradigm -- The immune system, pre-network paradigms -- The necessity for an interactive theory of immunity -- Proto-ideas of the network theory: antibody self-regulation, idiotypy, the brain analogy, and cybernetics -- The idiotypic network theory -- The T cell receptor puzzle -- Suppression turned idiotypic -- Network mannerism -- Post-network immunology: Idiotypic network continues at the bedside -- Hindsight -- Science between Fact and Fiction -- The fictional nature of scientific notions -- Fiction turned fact: The case of antibodies -- The enticing network: Fiction forever -- Logic and laws in life science
Control code
ocn406518778
Dimensions
unknown
Extent
1 online resource (vi, 274 pages)
Form of item
online
Isbn
9783764383732
Lccn
2008930062
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations
http://library.link/vocab/ext/overdrive/overdriveId
978-3-7643-8372-5
http://library.link/vocab/recordID
.b23597240
Specific material designation
remote
System control number
  • (OCoLC)406518778
  • pebcs3764383720

Library Locations

    • Deakin University Library - Geelong Waurn Ponds CampusBorrow it
      75 Pigdons Road, Waurn Ponds, Victoria, 3216, AU
      -38.195656 144.304955
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