The Resource Drugs and Pregnancy
- Drugs and Pregnancy
- Statement of responsibility
- BP Sheth
- Case reports and individual experiences are the sources of most information regarding ophthalmic medication use in human pregnancy. Although animal studies have been performed in teratologic research, it is difficult to extrapolate the data to humans because the metabolism of drugs varies in animal species and the doses of medications are usually much greater than those used clinically. In addition to the systemic effects of oral medications, topical medications can also be absorbed systemically and be secreted in breast milk. The ophthalmologist needs to consider the potential side effects of the medications on the pregnant patient, depending on the stage of pregnancy, as well as the possible adverse effects on the fetus and nursing baby. This module reviews the use of diagnostic and therapeutic ophthalmic drugs during pregnancy, the FDA's drug classification system regarding medication use in pregnancy and potential level of risk to the fetus, and methods to limit systemic absorption of topically applied medications
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